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PURPOSE: In this clinical study, it was aimed to prospectively evaluate the cochlear nerve with brainstem evoked response audiometry (BERA) in terms of audiological ailments in patients with COVID-19. Although the relationship of COVID-19 with tinnitus and hearing loss has been investigated since the day this infectious respiratory disease emerged, its relationship with BERA has not been fully demonstrated from a neurological perspective. METHODS: It was carried out on a group of patients who had COVID-19 in the last 6 months between February and August 2021 in Diyarbakir Gazi Yasargil Training and Research Hospital. Patients between the ages of 18-50, who applied to the otorhinolaryngology and neurology clinic and had COVID-19 in the last 6 months, were selected. The COVID-19 group of our study consisted of 30 patients, 18 males and 12 females, who had had COVID-19 disease in the last 6 months, and 30 healthy individuals, 16 males and 14 females, as the control group. RESULTS: In patients with COVID-19, the evaluation of the destruction of the cochlear nerve with BERA showed that there was a statistically significant prolongation in I-III and I-V interpeaks at 70, 80 and 90 db nhl. CONCLUSIONS: Statistically significant prolongation of especially I-III and I-V Interpeaks in BERA showed that COVID-19 has the potential to cause neuropathy. We believe that the BERA test should be considered in the neurological evaluation of cochlear nerve damage in patients with COVID-19 as a differential diagnosis.
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Audiometry, Evoked Response , COVID-19 , Female , Male , Humans , Infant , Child, Preschool , Cochlear Nerve , Ambulatory Care Facilities , Brain StemABSTRACT
Background and Aim: Apart from the direct and immediate invasion of coronavirus to vital tissues such as the heart, the virus is also capable of damaging these tissues based on the host's genetic susceptibility. The present bioinformatic- based study aimed to determine the genes and related microRNAs that most likely to be associated with susceptibility rates for virus-induced cardiovascular vulnerabilities. Method(s): A deep search was scheduled in databases including Pubmed (Medline), Google Scholar, Web of Science, and Scopus databases to assess all microRNAs and targeted genes related to cardiovascular defects induced by the coronavirus. The bioinformatic professional software systems were employed to assess gene-microRNAs interactions and mechanisms involved in cardiovascular injury. Result(s): The coronavirus can induce cardiovascular defects by the three mechanisms of inducing cardiac fibrosis (by up-regulating miR-367-3p and down-regulating hsa-miR- 5692a), inducing hypertension (by up-regulating miR-18b- 5p), and inhibiting microvascular angiogenesis (by up-regulation of miR-18b-5p and down-regulating hsa-miR-5692a). Such processes can be triggered by the effects on NFAT5, CD69, and HGF expression. Conclusion(s): Considering the central role of the revealed microRNAs and their targeted genes in cardiovascular injuries induced by coronavirus, such microRNAs can be applied for finding a way to stabilize the host against virus attacks as well as genetically based treatment for the affected host. (Figure Presented).
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Research background: Environmental factors are not adequately addressed in organizational ecology studies. At the same time, it is known that the theory has not received enough attention except for North America, which is the emerging point. Purpose: We aim to examine macroeconomic connectedness between the organizational ecology of transportation and storage firms and macroeconomic variables such as price and production indexes. Research methodology: This paper discusses the relation among the following variables within the framework of macroeconomic connectedness via organizational ecology theory. The variables are FOUNDINGS, DISBANDINGS, TRNSP-CPI, PPI IPI and ENERGY. We use the TVP-VAR based Diebold-Yllmaz Connectedness approach in the analysis of the data. Results: DISBANDING is the net transmitter throughout the entire period. FOUNDING is mainly a net shock receiver during the COVID-19 period and transmitter in other periods. TRANS-CPI and PPI are risk receivers throughout the entire period, and even the shocks they transmit increased in the post-2018 period. ENERGY and IPI are in shock receiver status throughout the entire period. The received shocks of IPI from others have decreased with the effect of the lockdown experienced during the COVID-19 period. Novelty: The investors can hedge against risk by looking at industry production capacity and the number of firm closures, considering the net bilateral link between the indices, and calculating the appropriate time period for establishing a firm. Connectedness indices vary considerably over the sampling period, which indicates that investors must dynamically adjust their position in the industry. © 2022 Murathan Tuncer et al., published by Sciendo.
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Purpose - In this study, visitors' attitudes and behavioural intentions towards camping/glamping tourism in Turkey during the pandemic were investigated using the extended theory of planned behaviour (TPB). The model has been extended to include constructs such as risk perception and risk aversion attitudes that stem from COVID-19 to predict visitors' attitudes and behavioural intentions. Design/methodology/approach - The data were collected through an online questionnaire from 432 participants who have experience and interest in camping/glamping tourism in Turkey. The responses were analysed using the structural equation modelling (SEM). Findings - The findings show that besides the basic TPB structures, other added variables also significantly affect visitors' attitudes and intentions. Moreover, it has been observed that the risk perception and risk aversion attitude derived from COVID-19 increase negative emotions in visitors and decreased behavioural intentions. Research limitations/implications - The results of the study are discussed for future research as well as its academic and practical implications. Originality/value - This theoretical expansion is thought to increase the theory's predictive power in predicting visitors' behaviour during the pandemic.
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OBJECTIVE: This study aimed to evaluate the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission risk and the oral hygiene behaviors of patients using removable dentures. STUDY DESIGN: A total of 220 removable dental prosthesis users were included in the study. Among them, 110 users diagnosed with the coronavirus disease were included in the case group and 110 unaffected users were included in the control group. A survey regarding their hygiene, prosthesis removal, and handwashing attitudes was completed by the participants. Measurable variables are presented as mean +/- standard deviation (SD) and categorical variables as numbers and percentage (%). RESULTS: Individuals in the case group had a significantly lower rate of handwashing with soap and water before prosthesis removal. Additionally, no significant difference was found between the frequencies of den ture removal between the 2 groups. Furthermore, individuals who removed their prostheses more than 2 times a day had an increased rate of handwashing with soap and water. CONCLUSION: To prevent the transmission of SARS-CoV-2, proper hand hygiene is important among individuals wearing removable dentures. Individual hand hygiene habits can affect transmission of the virus. Furthermore, dentists should educate their patients wearing removable dentures regarding proper hand hygiene and denture care to prevent further spread of the virus.
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In this study, we scientifically examined the consultations of the patients being hospitalized from the other departments to the cardiology department during Coronavirus Disease 2019 (COVID-19) pandemia. Consultations to the cardiology department between 01 April-31 May 2020 and 01 April-31 May 2019 were discussed. Demographic characteristics and reasons of consultations were compared. A different approach was f ollowed in COVID-19 patients diagnosed with compared to patients in other clinics. The rate of consulted patients in 2019 year was 14.4% (866/5989). Its rate in 2020 year was found as 18.5% (462/2486) (p: <0.001). A statistically significant difference was obtained in both groups. The use of drugs prolonging the Qt, preoperative and increase in cardiac enzymes were found statistically significant in terms of the consultations (p: <0.001-<0.001-0.003-0.016, respectively). Face to face interviews were made in 29% (33/114) of the patients who were consulted from COVÍD-19 clinics. In 71% (81/114) patients, electrocardiography (ECG) s were evaluated digitally. In this study, although there was a decrease in the number of hospitalized patients during the COVÍD-19 pandemia, we observed an increase in the number of patients being consulted to cardiology clinic. The relationship between COVÍD-19 disease and cardiovascular diseases and drugs being used in the treatment increased the workload of the cardiology clinic during the pandemic period.
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OBJECTIVE: COVID-19 can cause lung damage and may present with pneumonia in patients. In the present study, the correlation between the severity of pneumonia and electrocardiography parameters of COVID-19 were examined. METHODS: A total of 93 COVID-19 patients and a control group consisting of 62 volunteers were studied. Computed thorax tomography evaluation was performed;each lung was divided into three zones. For each affected zone, scores were given. The main computed thorax tomography patterns were described in line with the terms defined by the Fleischner Society and peer reviewed literature on viral pneumonia. We compared Computed thorax tomography of patients with corrected QT (QTc) and P wave dispersion (Pd) time. RESULTS: There is a significant difference between the patient and control groups in terms of QTc values (413.5+/-28.8 msec vs. 395.6+/-16.7 msec p<0.001). Likewise, the Pd value of the patient group is statistically significantly higher than that of the control group (50.0+/-9.6 ms computed thorax tomography ec vs. 41.3+/-5.8 msec p<0.001). In the patient group, a reverse correlation was detected between computed thorax tomography score and Pd value according to partial correlation coefficient analysis (correlation coefficient: -0.232, p=0.027). In the patient group, the correlation between computed thorax tomography score and QTc value was similarly determined according to partial correlation coefficient analysis (Correlation coefficient:0.224, p=0.017). CONCLUSIONS: COVID-19 prolongs QTc and P wave dispersion values;and as the severity of pneumonia increases, QTc value increases. However, whereas the severity of pneumonia increases, P wave dispersion value decreases.